Serum Tear Production for Dry Eyes
Alexander Martin, OD, FAAO
Boston Vision

This instructional video outlines the production of autologous serum tears for patients with severe dry eye disease (DED) unresponsive to conventional treatments. Derived from the patient’s own blood, serum tears offer biological components absent in artificial substitutes, such as growth factors and immunoglobulins. The process involves blood collection, coagulation, centrifugation, dilution with balanced salt solution, and sterile storage. Though preparation requires specialized equipment and presents logistical challenges, autologous serum tears provide a personalized, biologically compatible option for refractory DED. The video guides clinicians through each production step, supporting informed adoption of this advanced therapeutic approach in clinical practice.